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Our New Resource Page for CNS Neuroblastoma, FOXR2-Activated

by fatima.shakeel@opmc.co

CNS Neuroblastoma, FOXR2-Activated is a rare cancerous brain tumour that mainly affects children. It develops from immature nerve cells in the brain and is caused by changes that activate a gene called FOXR2, which helps the tumour grow. It usually...

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Our New Resource Page for EWSR1::SMAD3 Rearranged Fibroblastic Tumour

by fatima.shakeel@opmc.co

EWSR1::SMAD3 Rearranged Fibroblastic Tumour is a rare and recently recognised soft tissue tumour. It usually develops in the fingers, toes, feet, or hands. It is considered a benign (non-cancerous) tumour, but it can come back after treatment if it...

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Our New Resource Page for Sclerosing Angiomatoid Nodular Transformation (SANT)

by fatima.shakeel@opmc.co

Sclerosing Angiomatoid Nodular Transformation (SANT) is a rare, non-cancerous condition that affects the spleen. It involves the formation of abnormal blood vessel nodules surrounded by fibrous tissue. Although it is benign, it can sometimes appear...

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Our New Resource Page for CNS Tumour with BCOR/BCORL1 Fusions

by fatima.shakeel@opmc.co

CNS Tumour with BCOR/BCORL1 Fusions is a very rare and aggressive brain tumour. It develops because of abnormal changes (fusions) involving the BCOR or BCORL1 genes. This tumour is different from the more common CNS tumou with BCOR internal tandem...

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Our New Resource Page for CNS Tumour with BCOR Internal Tandem Duplication (BCOR-ITD)

by fatima.shakeel@opmc.co

CNS Tumour with BCOR Internal Tandem Duplication (BCOR-ITD) is a rare type of brain cancer that mostly affects babies and young children. It develops because of a change (mutation) in a gene called BCOR, which normally helps control how cells grow...

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Our New Resource Page for NTRK-Rearranged Spindle Cell Neoplasm

by fatima.shakeel@opmc.co

NTRK-Rearranged Spindle Cell Neoplasm is a rare type of soft tissue tumour. It develops because of a change (fusion) in a gene called NTRK. This genetic change causes cells to grow and divide abnormally, leading to the formation of a tumour. These...

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Our New Resource Page for CIC-DUX4 Sarcoma

by fatima.shakeel@opmc.co

CIC-DUX4 Sarcoma is a rare and aggressive cancer that usually develops in the soft tissues of the body, especially in the arms, legs, trunk, or deep muscles. It mainly affects children and young adults, although it can occur at any age. The tumour...

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Our New Resource Page for DICER1 Syndrome-Associated Sarcoma

by fatima.shakeel@opmc.co

DICER1 Syndrome-Associated Sarcoma is a rare type of cancer linked to changes in the DICER1 gene. The DICER1 gene normally helps control how cells grow and develop. When this gene is damaged, abnormal cells can grow and form tumours. These cancers...

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Our New Resource Page for Hepatic Epithelioid Angiosarcoma (HEA)

by fatima.shakeel@opmc.co

Hepatic Epithelioid Angiosarcoma (HEA) is a very rare and aggressive cancer of the liver. It develops from the cells that line blood vessels in the liver, called endothelial cells. It is a subtype of angiosarcoma in which the cancer cells look more...

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Our New Resource Page for Polymorphous Adenocarcinoma (Salivary Gland)

by fatima.shakeel@opmc.co

Polymorphous Adenocarcinoma is a rare cancer of the minor salivary glands. It usually develops inside the mouth, especially on the roof of the mouth (hard palate). This tumour grows slowly and often behaves less aggressively than many other...

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