What is Testicular Mixed Choriocarcinoma and Embryonal Carcinoma?
Testicular Mixed Choriocarcinoma and Embryonal Carcinoma is a malignant mixed germ cell tumour originating in the testicles. It is distinctively marked by the presence of both choriocarcinoma and embryonal carcinoma cell types. Germ cell tumours are derived from germ cells, which are the cells that develop into sperm in men. These cells are normally found in the testicles but can sometimes be found in other parts of the body if they migrated improperly during fetal development. Mixed germ cell tumours contain more than one type of germ cell cancer. In the case of Testicular Mixed Choriocarcinoma and Embryonal Carcinoma, the tumour contains both choriocarcinoma and embryonal carcinoma cells. Choriocarcinoma is a highly malignant form of germ cell tumour, characterized by the presence of cytotrophoblasts and syncytiotrophoblasts, the cells responsible for the formation of the placenta during pregnancy. It is very aggressive and can spread quickly throughout the body, often leading to symptoms caused by metastasis to other organs, such as the lungs. Embryonal carcinoma, on the other hand, is a primitive type of germ-cell tumour that resembles early embryonic tissue. While it is less aggressive than choriocarcinoma, it can still spread to other parts of the body if not treated in a timely manner.Symptoms
Symptoms of testicular mixed choriocarcinoma and embryonal carcinoma can include:- A lump in one of the testicles
- Testicular pain or discomfort
- Swelling in the testicles
- Lower back pain or shortness of breath if the cancer has spread to the lungs
- Unusual hormonal changes, which can cause symptoms like gynaecomastia (enlarged breasts in males)
Disease Aetiology (Causes)
The exact cause of testicular mixed choriocarcinoma and embryonal carcinoma is unknown. Some known risk factors for testicular cancer include a family history of the disease, having an undescended testicle, or abnormal testicle development.Diagnosis
Diagnosis of testicular mixed choriocarcinoma and embryonal carcinoma often involves:- Taking a detailed medical history and performing a physical examination
- Conducting an ultrasound of the scrotum to see the internal structures of the testicles
- Doing blood tests for tumour markers, like alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH)
- Carrying out a biopsy, where a small sample of testicular tissue is removed and examined under a microscope
Treatment
The treatment for testicular mixed choriocarcinoma and embryonal carcinoma typically includes:- Surgery: Orchiectomy, the surgical removal of the affected testicle, is the primary treatment.
- Chemotherapy: This treatment method is often used after surgery to kill any remaining cancer cells. It’s also used to treat advanced or metastatic cases.
- Radiation Therapy: While it’s not the first line of treatment for these types of testicular cancer, it may be used in certain circumstances.
What Support can we Give for Testicular Mixed Choriocarcinoma and Embryonal Carcinoma?
Testicular Mixed Choriocarcinoma and Embryonal Carcinoma is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Testicular Mixed Choriocarcinoma and Embryonal Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please get in touch with us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
