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Choriocarcinoma with Teratoma of the Testis – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Jul 3, 2023

What is Choriocarcinoma with Teratoma of the Testis?

Choriocarcinoma with teratoma of the testis is a mixed germ cell tumour, which is a rare and aggressive variant of testicular cancer. It consists of two distinct types of cancer cells: choriocarcinoma and teratoma. Choriocarcinoma cells are highly malignant and originate from trophoblastic cells, which form the placenta in a normal pregnancy. Teratoma cells are a type of germ cell tumour that can contain several different types of tissues, such as hair, muscle, or bone. It falls under the category of nonseminomatous germ cell tumours.

Symptoms

The symptoms of choriocarcinoma with teratoma of the testis can include:

  • A lump in the testicle
  • Testicular pain or discomfort
  • Swelling of the testicles
  • Lower back pain or shortness of breath if the cancer has spread to the lungs
  • Unusual hormonal changes leading to symptoms like gynaecomastia (enlarged breasts in males)

Disease Aetiology (Causes)

While the exact cause of choriocarcinoma with teratoma of the testis is unknown, certain risk factors are associated with testicular cancer in general. These include having a family history of the disease, having an undescended testicle, or experiencing abnormal development of the testicles.

Diagnosis

The diagnosis of choriocarcinoma with teratoma of the testis generally involves:

  • Detailed medical history and physical examination
  • An ultrasound scan of the scrotum to visualise the internal structures of the testicles
  • Blood tests for tumour markers, such as alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH)
  • Biopsy, in which a small sample of testicular tissue is removed and examined under a microscope

Treatment

The treatment plan for choriocarcinoma with teratoma of the testis often includes:

  • Surgery: The primary treatment option is orchiectomy, which involves the surgical removal of the affected testicle.
  • Chemotherapy: Post-surgical treatment usually involves chemotherapy to kill any remaining cancer cells.
  • Radiation therapy: This is typically not the first line of treatment for these types of testicular cancer, but it may be considered under certain circumstances.

What Support can we Give for Choriocarcinoma with Teratoma of the Testis?

Choriocarcinoma with Teratoma of the Testis is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Choriocarcinoma with Teratoma of the Testis, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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