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Synovial Sarcoma – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Feb 2, 2024

 

What Is Synovial Sarcoma?

Synovial sarcoma is a rare type of cancer that usually arises near the joints of the arm, neck, or leg, but it can occur anywhere in the body. Despite its name, it does not originate from synovial tissue (the lining of joint cavities) but from cells that are not fully understood and might be related to stem cells. Synovial sarcoma is more common in young adults but can affect individuals of any age. It is characterized by the formation of a slow-growing lump or mass, which can be painful and may restrict movement.

Symptoms

Symptoms of synovial sarcoma often depend on the tumour’s size and location but typically include:

  • A noticeable lump or swelling, which may or may not be painful
  • Pain or soreness caused by the tumour pressing against nerves or muscles
  • Restricted movement if the tumour is near a joint
  • Numbness or tingling in the affected limb if the tumour affects nerve tissue

Disease Aetiology (Causes)

The exact cause of synovial sarcoma is unknown, but it involves genetic mutations. Specifically, a translocation between chromosomes X and 18 is commonly associated with this cancer. These genetic changes are usually not inherited but occur spontaneously.

Diagnosis

Diagnosing synovial sarcoma involves several steps:

  • Imaging tests, such as MRI, CT scans, and X-rays, to determine the tumour’s size and location
  • A biopsy, where a sample of the tumour tissue is examined under a microscope to confirm the presence of cancer cells
  • Genetic tests to identify the characteristic chromosomal translocation associated with synovial sarcoma

Treatment

Treatment for synovial sarcoma typically includes a combination of therapies:

  • Surgery to remove the tumour along with a margin of healthy tissue around it, which is the primary treatment method to ensure complete removal of the cancer.
  • Radiation therapy may be used before or after surgery to reduce the risk of recurrence, especially if complete surgical removal is challenging.
  • Chemotherapy is often recommended for larger tumouurs, tumours that have spread, or to shrink the tumour before surgery.
  • Targeted therapy and immunotherapy are emerging treatment options being explored in clinical trials.

What support can we give for the Synovial Sarcoma?

Synovial Sarcoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Synovial Sarcoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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You can help us with your donation:

Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:

Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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