What is Somatostatinomas of the Pancreas?
Pancreatic somatostatinoma is a rare type of endocrine tumour that arises from delta cells in the pancreas that secrete a hormone called somatostatin. The hormone somatostatin regulates many physiological functions in the body and inhibits the secretion of other hormones. Somatostatinomas are hormones that secrete somatostatin, these tumours secrete an excess amount of somatostatins, more than the body needs. It shows a good prognosis with treatment.
There is no well-known cause; however certain hereditary and genetic conditions such as multiple endocrine neoplasia type1, Von-Hippel-Lindau Disease, neurofibromatosis and tuberous sclerosis are the risk factors for the development of somatostatinomas of the pancreas. It usually develops in people in their 50s, 60s, or 70s.
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- Pain in the abdomen
- Excessive hunger
- Unexplained weight loss
- Diabetes ( increased blood sugar levels)
- The fatty stool which is difficult to flush out
- Gall stones
- Loss of appetite
- Blood with stool while defecation
The following diagnostic tests and procedures can be used to make a diagnosis; these are
- Imaging techniques like CT-scan, MRCP (magnetic resonance cholangiopancreatography), MRI, TUS (transcutaneous ultrasonography), and PET-scan.
- Endoscopic USG
- CBC ( complete blood count)
- BSR( Blood sugar random), Fasting blood sugar, and GTT ( glucose tolerance test)
- Histopathological examination of the pancreatic cell’s tumour
- Raised serum alpha-fetoprotein
The main treatment is surgery (surgical removal of the cancerous part of the pancreas and the other tumour sites). Chemotherapy and radiotherapy are treatment options for advanced metastatic cases.
What Support can we Give for Somatostatinomas of the Pancreas?
Somatostatinomas of the Pancreas is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Somatostatinomas of the Pancreas, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
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