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Retinoblastoma (Eye) – Symptoms, Treatment & Support

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Posted by adeel | Oct 18, 2020

What is Retinoblastoma?

Retinoblastoma is a rare type of cancer in the innermost layer of the eye called the retina. The retina is made up of photoreceptors and neuronal cells. These photoreceptors receive light, convert it into electrical signals, and send those signals to the brain to complete the visual process of creating vision.

Disease Epidemiology

The global incidence of retinoblastoma is 11 per million young children under 5 years of age. According to a scientific report, the survival rate for retinoblastoma patients ranges from 86% to 92%. Most often diagnosed in children under 5 years of age.

Disease Etiology

Genetic mutation is the main cause of the development of retinoblastoma.

Signs and symptoms

The patient may suffer from the following signs and symptoms. These are
  • When light is thrown on the eye a white centre circle appears on the eye. It is known as the cat’s eye reflex.
  • Red, painful eye 
  • Glaucoma (Increased intraocular pressure of the eye)
  • Poor vision
  • Repetitive uncontrolled movement of the eyes
  • Loss of appetite
  • Weight loss

  Diagnosis

The following diagnostic tests and procedures can be used to make a diagnosis.
  • Complete blood count (CBC), Urine complete examination (UCE), LFT’s (Liver function tests) to rule out other diseases confused with retinoblastoma.
  • DNA analysis
  • Aqueous humour enzyme level assays
  • Imaging techniques like USG, X-RAY, CT-scan, MRI, and PET-scan to know the size, site, and extent of the tumour.
  • Immunohistopathologic staining
  • Dilated fundus examination with indirect ophthalmoscopy
  • Bone marrow aspiration and biopsy

Treatment

The treatment options are;  
  • Chemotherapy
  • External beam radiation therapy (for tumours that tend to grow during chemotherapy)
  • Radioactive isotope plaque (radioactive isotope plaque treatment is recommended for one large retinoblastoma or more than one moderate-sized tumours).
 
 

What Support can we Give for Retinoblastoma (Eye)?

Retinoblastoma (Eye) is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Retinoblastoma (Eye), we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

Sign Up

You can help us with your donation:

Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
 

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