What is primary cardiac angiosarcoma?Primary cardiac angiosarcoma is a rare type of soft tissue sarcoma that arises from the cells that make up the blood vessels of the heart. Primary cardiac angiosarcoma is an extremely rare type of tumour that is malignant (cancerous) in nature and tends to invade local tissues and metastasize (spread) to other parts of the body. It is commonly developed in the right upper chamber of the heart also called the right atrium.
Disease EpidemiologyIt is a rare tumour with an incidence of 0.0001- 0.030%. It is more common in men than women. It mainly affects people under the age of 65. The prognosis is poor; the 5-year survival rate is 14%.
Disease EtiologyThere is no well-known cause, however, certain genetic mutations are considered responsible.
Signs and symptomsSigns and symptoms depend on the location or part of the origination heart sarcoma. Common signs and symptoms in patients with cardiac sarcoma are
- Difficulty in breathing on exertion or any physical activity, or during sleep
- Syncope (Sudden loss of consciousness)
- Palpitations (sensation of feeling your heartbeat)
- Coughing up blood or blood-stained mucous
- Night sweats
- Weight loss
- Pain in joints
- The feeling of constant tiredness
- Swelling of neck veins, legs, abdomen and ankles
- Sudden death due to cardiac arrest
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis. These are
- Echocardiogram (Ultrasonography of the heart)
- X-ray Chest
- MRI of heart
- CBC (complete blood count)