What is Mediastinal Pheochromocytoma?
Mediastinal pheochromocytoma is a rare type of mediastinal tumor that develops from chromaffin cells of the sympathetic nervous system. Chromaffin cells are found along the aortic ganglia in the chest or mediastinum. In most cases, chromaffin cells originate from the adrenal glands of the kidneys; however, in 1% of cases, extraadrenal pheochromocytoma arises from the chest or mediastinum, known as mediastinal pheochromocytoma or mediastinal paraganglioma.What is Mediastinum?
The mediastinum is a space in the thorax that contains the heart, thymus gland, portions of the esophagus trachea, and other structures.Disease Causes
There is no well-known cause, but certain hereditary and genetic conditions may be responsible for the development of mediastinal paraganglioma.Signs and Symptoms
Most patients with mediastinal paraganglioma show no signs and symptoms; however, in a few cases, the patient may show the following signs and symptoms. These are- Persistent headache
- High blood pressure
- Excessive Sweating
- Rapid heartbeat
- Pain in the chest
- Anxiety
- Nausea
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are- CBC (complete blood count)
- Blood sugar levels
- Measurement of plasma-free metanephrines
- CT-scan, MRI, OR PET Scan of abdomen and chest
Treatment
Complete surgical resection (surgical removal of the part or whole of the tumor or affected organ) of the tumor is the main treatment option. Blood pressure can be controlled before surgery by prescribing alpha-blockers, beta-blockers, calcium channel blockers, and ACE inhibitors.What Support can we Give for Mediastinal Pheochromocytoma?
Mediastinal Pheochromocytoma is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Mediastinal Pheochromocytoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
