What is Immunoblastic Diffuse Large B-cell Lymphoma?
Immunoblastic Diffuse Large B-cell Lymphoma (DLBCL) is a subtype of non-Hodgkin lymphoma characterized by the rapid growth of large B lymphocytes, often showing an immunoblastic morphology. This aggressive lymphoma can affect various organs and tissues throughout the body, including the lymph nodes, spleen, and bone marrow, as well as extranodal sites.
Symptoms
The symptoms of Immunoblastic Diffuse Large B-cell Lymphoma may include:
- Swelling of lymph nodes, typically painless (in the neck, armpits, or groin).
- Unexplained weight loss.
- Fever and night sweats.
- Fatigue and a feeling of being unwell.
- Loss of appetite.
- Breathlessness or cough if the lymphoma involves the chest area.
- Abdominal pain or swelling if the abdomen is affected.
Disease Aetiology (Causes)
The precise causes of Immunoblastic Diffuse Large B-cell Lymphoma are not fully understood, but the following factors may contribute to its development:
- Genetic mutations in B lymphocytes.
- Environmental factors.
- A history of certain infections or immune disorders.
Diagnosis
Diagnosing Immunoblastic Diffuse Large B-cell Lymphoma generally involves:
- Physical Examination: Checking for swollen lymph nodes and other signs of lymphoma.
- Blood Tests: To look for markers indicating lymphoma.
- Imaging Tests: Such as CT scans, PET scans, and X-rays to identify the extent of the disease.
- Biopsy: Taking a sample from the lymph node or affected tissue for pathological examination.
Treatment
Treatment options for Immunoblastic Diffuse Large B-cell Lymphoma can include:
- Chemotherapy: The primary treatment modality, often combined with immunotherapy.
- Radiation Therapy: Used in certain cases, especially for localized disease.
- Immunotherapy: Drugs like rituximab are used in combination with chemotherapy to enhance the treatment’s effectiveness.
- Stem Cell Transplantation: Considered in cases of relapse or high-risk patients.
What support can we give for Immunoblastic Diffuse Large B-cell Lymphoma?
Immunoblastic Diffuse Large B-cell Lymphoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Immunoblastic Diffuse Large B-cell Lymphoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
