What is Glioblastoma?Glioblastoma is a type of brain cancer that develops from glial cells in the brain. Glial cells are cells that support the internal environment of the brain and spinal cord, provide nutrition and protection. It is aggressive cancer with a 5-year survival rate of 5-7%. It also tends to relapse.
What is Glioblastoma Multiforme?A glioblastoma is an aggressive form of glioblastoma cancer. It is a collection of cancerous cells originating from glial cells in the brain and spinal cord. It is a common and aggressive cancer with a survival rate of less than 1 year. We called it multiforme because it causes multiple hemorrhages and cell death in the brain and spinal cord, which leads to the rapid progression of the disease.
Disease Etiology (Causes)There is no well-known cause; however previous exposure to radiation or radiation therapy and certain genetic disorders (diseases) such as neurofibromatosis and Li-Fraumeni syndrome are the risk factors that can cause glioblastoma. Disease Epidemiology Glioblastoma multiform is more common in adults than children.
Signs and SymptomsThe initial signs and symptoms of the glioblastoma multiforme are mentioned below.
- Constant headache
- Changes in mood and behavior
- Blurred vision
- Difficulty in speaking
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging tests such as X-Ray, CT-scan (computerized tomography), PET-scan (Positron emission tomography) help detect the site, size, and location of the tumor.
- Tumor biopsy and histopathological examination