What is Giant Cell Carcinoma of the Renal Pelvis?
Giant cell carcinoma of the renal pelvis is a rare type of benign tumour that arises from the central part of the kidney. Giant cell carcinomas usually arise from joints close to the bones and, rarely, from the soft tissues of body organs. Other sites for the development of giant cell carcinoma are the breast, skin, soft tissues, salivary glands, lungs, pancreas, female genital tract, thyroid, larynx, and heart. Giant cell carcinoma of the renal pelvis is usually a benign tumour and does not spread to other distant parts of the body.Disease Causes
There is no well-known cause, however, certain hereditary and genetic mutations are considered responsible for the development of giant cell carcinoma of the renal pelvis.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Pain in the back
- Mass on side of the back
- Blood in the urine
- Frequent desire to pass urine
- Pain while passing urine
- Unintentional weight loss
- Constant Fever
- Constant Fatigue
- Loss of appetite
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are- Physical examination and complete medical history
- Ultrasound (USG), CT scan, MRI, and PRET-scan of the abdomen
- Biopsy of the lesion/tumour and histopathological examination
- Barium Meal
- Renal functions tests (RFTs)
- Liver function tests (LFTs)
- Complete blood count (CBC)