What is Verrucous carcinoma (Vulva)?Vulvar verrucous carcinoma is a very rare subtype of abnormal squamous cell growth. Verrucous carcinoma (vulva) accounts for less than 1% of malignant neoplasms in women. The term vulva is used to refer to the external female genitalia. The most commonly affected sites are labia major (the outer lip of vulva) and labia minora (the inner lip of vulva).
Disease EpidemiologyIt accounts for less than 1% of malignant neoplasms in women. The incidence rate in the world is 1-3 cases per 100,000 women. In 85% of cases, it develops in women aged 60 to 70 years, and in 15% of cases in women aged 40 years. It usually affects the local area but does not spread to other regions or distant parts of the body. It appears to be like a large cauliflower with ulceration and bleeding.
Disease Etiology (Causes)There is no exact- well-known cause. Initially, it was associated with Human papillomavirus (HPV) infection.
Signs and symptomsThe patient may suffer from following signs and symptoms. These are;
- A slowly growing firm mass
- Itching at Vulva
- Pain at the site of tumour and vulva
- Discharge from vulva or vagina
- Ulceration in tumour
- Bleeding from mass or abnormal growth at the vulva
DiagnosisDefinite diagnostic tests to diagnose the vulvar verrucous carcinoma (vulva) are tumour biopsy, histopathology, and cytogenetic study of the specimen. Radiological techniques like CT scan, MRI, USG, and X-ray also recommended locating the size and site of the tumour.
- Simple, partial, or radical vulvectomy (surgical removal of the entire or tumour portion of the vulva) with or without surgical removal of the femoral and inguinal lymph nodes depending on the extent of the tumour