What is Transitional Cell Carcinoma of the Renal Pelvis?Transitional cell cancer of the renal pelvis is a rare type of cancer that originates from the transitional epithelial cells of renal pelvis. It is the most common cancer of the renal pelvis.
Disease CausesThere is no well-known cause, however, certain hereditary or genetic mutations are considered responsible for the development of renal transitional cell carcinoma. Cigarette smoking, kidney stones, Urinary bladder stones, chronic bacterial infection, and unnecessary use of pain relievers are risk factors for developing transitional cell carcinoma of the renal pelvis and ureter.
Disease EtiologyTransitional cell carcinoma of the renal pelvis most often develops in people aged 60-70 years. It is more common in men than in women, the incidence in men is 2 times higher than in women. It is more common in people of African American origin.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- It is usually asymptomatic and is found incidentally in most patients.
- However, in symptomatic cases, the patient may suffer from the presence of blood in the urine, pain in the pelvic region.
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis. These are
- Blood tests such as Complete blood count (CBC)
- Urine complete examination (Urine test)
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Tumor biopsy