What is Transitional Cell Carcinoma with Adenocarcinomatous Differentiation of the Renal Pelvis?Transitional cell carcinoma of the renal pelvis with adenocarcinoma changes is a type of cancer that arises from the transitional epithelial cells that make up the inner lining of the renal pelvis and ureter along with adenocarcinoma cells. Adenocarcinoma cells usually grow in tubules and very rarely develop in the renal pelvis.
What is Renal Pelvis?The renal pelvis is the site of the kidney where all urine is collected, then filtered through it, and through the ureters collects into the bladder. Small cell carcinoma of the renal pelvis is more common in women than in men.
Disease CausesThere is no well-known cause; however certain hereditary and genetic mutations (a change in the sequence of DNA or genetic material) are considered potential causes for the development of small cell carcinoma of the renal pelvis. Cigarette smoking and chronic inflammation of the kidneys are also contributing risk factors for the development of small cell carcinoma of the renal pelvis.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Pain in the back
- Mass on side of the back
- Blood in the urine
- Frequent desire to pass urine
- Pain while passing urine
- Unintentional weight loss
- Constant Fever
- Constant Fatigue
- Loss of appetite
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis. These are
- Blood tests such as Complete blood count (CBC)
- Urine complete examination (Urine test)
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Tumor biopsy