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Renal Cell Carcinoma – Oncocytoma – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Jan 24, 2024

What Is Renal Cell Carcinoma – Oncocytoma?

Renal cell carcinoma – oncocytoma is a benign kidney tumour characterized by its rich content of mitochondria, giving the cells a distinctive granular appearance. Although oncocytomas are non-cancerous and typically do not spread to other parts of the body, their diagnosis is important as they can closely resemble certain types of renal cell carcinoma (RCC) under imaging studies. Oncocytomas account for a significant percentage of all renal tumours and are often discovered incidentally during imaging tests for other conditions.

Symptoms

Renal oncocytomas usually do not cause symptoms and are often found incidentally during imaging studies for unrelated health issues. In some cases, if the tumour grows large enough, it may cause:

  • A palpable mass in the abdomen or side.
  • Blood in the urine (hematuria).
  • Pain or discomfort in the side, back, or abdomen.
  • Unintentional weight loss (rare).

Disease Aetiology (Causes)

The exact cause of renal oncocytoma is not well understood. As with many tumours, genetic and environmental factors may play a role, but specific risk factors for oncocytoma have not been clearly identified.

Diagnosis

The diagnosis of renal oncocytoma often involves:

  • Imaging tests, such as ultrasound, computed tomography (CT) scans, and magnetic resonance imaging (MRI), to visualize the kidney and the tumour.
  • Biopsy, in which a sample of the tumour is taken and examined under a microscope, can help differentiate oncocytoma from malignant kidney tumours.
  • Blood and urine tests to assess kidney function and look for signs of other kidney diseases.

Treatment

Because renal oncocytomas are benign, treatment may not always be necessary. When intervention is required, options include:

  • Active surveillance, especially for smaller tumours, involves regular monitoring with imaging tests.
  • Surgery, such as partial nephrectomy, to remove the tumour while preserving as much kidney function as possible. Complete nephrectomy, removal of the entire kidney, is less common and typically reserved for larger or more complex tumours.
  • Ablative therapies, such as radiofrequency ablation or cryoablation, are minimally invasive options for some patients.

What support can we give for the Renal Cell Carcinoma?

Renal Cell Carcinoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Renal Cell Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:

Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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