What Is Paraganglioma of the Heart?
Paraganglioma of the heart is an extremely rare type of tumour that originates from the paraganglionic cells associated with the autonomic nervous system, which are found throughout the body, including in and around the heart. These tumours, part of a group known as neuroendocrine tumours, can produce catecholamines, which are hormones like adrenaline and noradrenaline, leading to various systemic symptoms.
Symptoms
Symptoms of cardiac paraganglioma can be varied and may mimic other cardiovascular conditions, including:
- High blood pressure, which may be difficult to control with standard treatments.
- Heart palpitations or arrhythmias.
- Chest pain or discomfort.
- Sweating, headaches, or panic attack-like symptoms due to excess catecholamine production.
- Fatigue or weakness.
Disease Aetiology (Causes)
The exact cause of paraganglioma, including those occurring in the heart, is not well understood, but they can be associated with:
- Genetic mutations, some of which may be inherited.
- A family history of paragangliomas or related conditions.
- Sporadic mutations with unknown triggers.
Diagnosis
Diagnosing a paraganglioma of the heart involves:
- Imaging studies such as MRI, CT scan, or echocardiography to identify the presence and location of the tumour.
- Biochemical tests to measure levels of catecholamines and their metabolites in the blood and urine.
- Genetic testing, especially if there is a family history of paraganglioma or related tumours.
Treatment
Treatment for paraganglioma of the heart focuses on managing symptoms and removing the tumour, when possible, through:
- Surgery, which is often the primary treatment option to remove the tumour completely.
- Medication to control symptoms caused by excess catecholamine production, such as high blood pressure.
- Radiation therapy or targeted therapy may be options in cases where surgery is not feasible or the tumour has spread.
What support can we give for the Paraganglioma of the Heart?
Paraganglioma of the Heart is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Paraganglioma of the Heart, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
