What Is Renal Cell Carcinoma – Clear Cell?
Renal cell carcinoma – clear cell (ccRCC) is the most common type of kidney cancer in adults, representing about 70-80% of all renal cell carcinomas. It’s named for the appearance of the cancer cells under a microscope, which are pale or clear due to the accumulation of lipids and carbohydrates in the cells. ccRCC originates in the lining of the proximal convoluted tubule, a part of the small tubes in the kidney that filter waste from the blood to produce urine.
Symptoms
The symptoms of clear cell renal cell carcinoma may not be noticeable in the early stages. As the tumour grows, symptoms may include:
- Blood in the urine (hematuria)
- Pain or a lump in the side or abdomen
- Unexplained weight loss
- Fever
- Fatigue
- High blood pressure
- Anemia
Disease Aetiology (Causes)
The exact cause of clear cell renal cell carcinoma is not fully understood, but several risk factors have been identified:
- Smoking
- Obesity
- High blood pressure
- Long-term dialysis
- Genetic factors, such as von Hippel-Lindau disease, which is associated with a higher risk of developing ccRCC
Diagnosis
Diagnosis of clear cell renal cell carcinoma involves:
- Imaging tests, such as ultrasound, computed tomography (CT) scans, and magnetic resonance imaging (MRI), to detect abnormalities in the kidney.
- Blood and urine tests to check for signs of kidney problems.
- A biopsy, in which a sample of kidney tissue is removed and examined under a microscope for cancer cells.
Treatment
Treatment for clear cell renal cell carcinoma depends on the stage of the cancer, the patient’s overall health, and other factors. Options may include:
- Surgery to remove the tumour or the entire kidney (nephrectomy), which is the primary treatment for localized cancer.
- Ablative therapies, such as cryoablation or radiofrequency ablation, for small tumours.
- Targeted therapy drugs that specifically attack certain abnormalities within cancer cells.
- Immunotherapy to boost the body’s natural defenses to fight the cancer.
- Radiation therapy and chemotherapy, which are less commonly used but may be options in certain situations.
What support can we give for the Renal Cell Carcinoma?
Renal Cell Carcinoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Renal Cell Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
