What is the Primary Astrocytoma of the Spinal Cord?
Primary astrocytoma of the spinal cord is a rare subtype of spinal cord tumor that arises from abnormal growth of glial cells that support and provide nutrition to the nerve cells originating from the brain and spinal cord. These are low-grade tumors and account for 6-8% of all spinal cord tumors. Low-grade tumors are those that grow slowly and usually do not spread to other distant parts of the body. However, astrocytoma of the spinal cord has the tendency to invade deeper tissues from its site of origin. It usually affects children and adults. It commonly develops in the 3rd decade of life with the mean age for the development of the disease being 30 years. Primary astrocytoma of the spinal cord more commonly affects males as compared to females with the M: F being 3:2. It more frequently develops in the chest and neck region of the spinal cord.Disease Causes
There is no well-known cause, but an increased association has been found between the presence of conditions such as neurofibromatosis type 1 and the development of a primary spinal cord astrocytoma.Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are- Pain in the back
- Altered states of consciousness
- Weakness in one or both sides of the body
- Numbness in arms and legs
- Difficulty in walking and writing, loss of voluntary control of muscles
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis. These are;- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumor.
- Tumor biopsy (tumor biopsy to remove a small sample of tissue for histopathological examination)
- USG-guided fine needle aspiration cytology