What is primary cerebral lymphoma?Primary cerebral lymphoma is a type of cancer that begins in the lymphatic tissues of the cerebral part of the brain. The cerebrum is the uppermost part of the brain; it consists of two hemisphere shaped lobes, separated by a fissure. The function of the brain is to initiate and coordinate body movements, as well as to perceive the sensations of touch, sight, hearing, taste, and temperature. It is an aggressive and fatal tumour that can lead to death within one to three months if not treated early.
What are Lymphoma and lymphatic system of the body?Lymphoma is a type of cancer in which cancer cells result from the rapid, uncontrolled division of certain types of white blood cells and form in the lymphatic system. The lymphatic system consists of lymph nodes, lymphatic vessels, tonsils, spleen, thymus, and bone marrow.
Disease Etiology (Causes)There is no well-known cause, but it is common in people with HIV (Human immune deficiency virus) and Epstein virus infection. It is more prevalent in older adults in their fifth or sixth decade of life. People over 50 are more likely to develop cerebral lymphoma.
Signs and symptomsThe patient may suffer from the following sign and symptoms. These are
- Impairment in vision or vision loss
- Paralysis of one side of the body
- Difficulty in walking
- Changes in behaviour
- Seizures (sudden uncontrolled changes in movements, feelings, or level of consciousness)
- Slurred speech
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging tests such as X-Ray, CT scan (computerized tomography), PET scan (Positron emission tomography) help detect the site, size, and location of the tumor.
- Complete blood count (CBC)
- Lumbar Puncture
- Tumour biopsy and histopathological examination