What is Plasmacytoma Brain?
A Plasmacytoma Brain is a rare, malignant tumour derived from plasma cells, which are responsible for producing antibodies in the body. While plasmacytomas most commonly appear in the bone marrow, especially within the spine or skull, their manifestation within the brain tissue itself is exceedingly uncommon.Symptoms
The symptoms linked with Plasmacytoma Brain are largely influenced by the size and exact location of the tumour:- Persistent or worsening headaches.
- Seizures or fits.
- Cognitive changes, including memory problems or difficulty concentrating.
- Focal neurological signs like weakness in specific body parts.
- Behavioural or mood alterations.
- Changes in vision or hearing.
- Nausea or vomiting, especially early in the morning.
Disease Aetiology (Causes)
The precise aetiology behind the development of the Plasmacytoma Brain remains unclear. It is believed to result from a single clone of plasma cells that start to grow uncontrollably.Diagnosis
The diagnostic approach for Plasmacytoma Brain typically involves:- Neurological Examination: This evaluates neurological health and the presence of specific symptoms.
- Imaging Studies: MRI is the primary tool for visualising soft tissue tumours like Plasmacytoma. CT scans can also be beneficial, especially if bone involvement is suspected.
- Biopsy: Extracting a tissue sample and examining it under a microscope is crucial for confirming the diagnosis.
Treatment
Potential treatments for Plasmacytoma Brain include:- Surgery: The primary goal would be to remove the tumour while preserving as much surrounding healthy brain tissue as possible.
- Radiation Therapy: This might be the primary treatment, especially if the tumour can’t be wholly removed surgically, or it could follow surgery to kill any lingering cancerous cells.
- Chemotherapy: Not always the first line of treatment for plasmacytomas, but can be considered based on the tumour’s specifics and its response to other therapies.