What is Malignant Fibrous Histiocytoma Brain?
Malignant Fibrous Histiocytoma Brain is an aggressive tumour type previously classified under soft tissue sarcomas. Modernly, it’s more commonly referred to as “undifferentiated pleomorphic sarcoma” when found in soft tissue. Its manifestation in the brain is extremely rare, presenting significant diagnostic and therapeutic challenges.Symptoms
Symptoms associated with Malignant Fibrous Histiocytoma Brain depend on the tumour’s size and location:- Persistent headaches
- Seizures
- Cognitive shifts or confusion
- Focal neurological issues, such as body-part specific weakness
- Behavioural or personality changes
- Vision problems
Disease Aetiology (Causes)
The exact cause of Malignant Fibrous Histiocytoma Brain remains undetermined. It’s believed to originate from primitive mesenchymal cells, but its cerebral manifestation’s specific risk factors remain undefined.Diagnosis
The diagnosis process for Malignant Fibrous Histiocytoma Brain includes:- Neurological Examination: To assess symptoms and overall neurological health.
- Imaging Studies: MRI and CT scans can pinpoint the size, location, and tumour attributes.
- Biopsy: Taking a tissue sample is crucial for a definitive diagnosis and differentiating it from other brain tumours.
Treatment
Treatment options for Malignant Fibrous Histiocytoma Brain include:- Surgery: Removing as much of the tumour as achievable is often the primary approach.
- Radiation Therapy: This might follow surgery to address remaining tumour cells or be the main treatment if surgery isn’t an option.
- Chemotherapy: Given the tumour’s aggressive nature, chemotherapy can tackle rapidly dividing cancer cells.