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Partial Hydatidiform Mole of the Uterus – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | Apr 24, 2023

What is a Partial Hydatidiform Mole of the uterus?

A partial hydatidiform mole of the uterus (also known simply as a partial molar pregnancy) is an abnormal pregnancy where an embryo is present but is typically malformed and unable to survive. This condition results from an abnormal conception where two sperm fertilise a single egg, leading to an embryo with an extra set of chromosomes. This chromosomal abnormality triggers an overgrowth of the placental tissue, forming a mass of cysts that resemble grape-like clusters. While it is not a form of cancer, in rare cases, a partial molar pregnancy can develop into a type of cancer known as a gestational trophoblastic disease (GTD).  

Disease Aetiology (Causes)

A partial hydatidiform mole is caused by abnormal fertilisation. Specifically, instead of the normal combination of one sperm and one egg, two sperm cells fertilise a single egg. This leads to an extra set of chromosomes in the embryo and triggers an overgrowth of placental tissue. Factors that may increase the risk of a molar pregnancy include maternal age (specifically women under 20 or over 35), a history of previous molar pregnancy, and certain dietary deficiencies.  

Diagnosis

Diagnosis of a partial hydatidiform mole of the uterus often involves:
  • Detailed medical history and physical examination
  • Ultrasound, which may reveal a cluster of cysts in the uterus
  • Blood tests to measure levels of human chorionic gonadotropin (hCG), a hormone typically elevated in molar pregnancies
 

Treatment

The treatment for a partial hydatidiform mole typically involves:
  • Dilation and curettage (D&C): A surgical procedure to remove abnormal tissue from the uterus. It’s the most common treatment for a molar pregnancy.
  • Monitoring hCG levels: Following the surgical treatment, hCG levels in the blood are regularly monitored until they return to normal, to ensure that all the molar tissue has been removed.

 

What Support can we Give for Partial Hydatidiform Mole of the Uterus?

Partial Hydatidiform Mole of the Uterus is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as the Partial Hydatidiform Mole of the Uterus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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