What is the Melanoma of the Vulva?
Melanoma of the vulva is a rare type of skin cancer that develops from melanocytes, the cells that produce melanin pigment in the skin. Although it represents a small percentage of all vulvar cancers, vulvar melanoma is a serious condition due to its potential to spread to other parts of the body.Symptoms
Symptoms of melanoma of the vulva can include:- A new mole or change in an existing mole on the vulva. This could involve changes in size, shape or colour, irregular borders, or an asymmetrical appearance.
- A lump or area of thickened skin on the vulva.
- Itching, pain or bleeding from a spot on the vulva.
- Changes in the skin of the vulva, such as discolouration or the appearance of a shiny, pearly nodule.
Disease Aetiology (Causes)
The exact cause of melanoma of the vulva is not known, but risk factors can include fair skin, a history of sunburn or frequent sun exposure, having many moles, and a family history of melanoma.Diagnosis
Diagnosis of melanoma of the vulva typically involves:- Detailed medical history and physical examination.
- Dermoscopy: a non-invasive, diagnostic tool that dermatologists use to examine skin lesions.
- Biopsy: a procedure to remove a small sample of suspicious skin for examination under a microscope.
- Imaging tests such as ultrasound, CT scan, or MRI to evaluate the extent of the cancer and to check for metastasis.
Treatment
The treatment for melanoma of the vulva often includes:- Surgery: The primary treatment is surgical removal of the melanoma and some of the normal tissue around it.
- Sentinel lymph node biopsy: A procedure to determine if the melanoma has spread to nearby lymph nodes.
- Immunotherapy: This type of drug treatment boosts the body’s immune system to fight cancer.
- Targeted therapy: These are drugs that target specific genes or proteins to help stop cancer from growing and spreading.