What Is Papillary Carcinoma of the Kidney?
Papillary carcinoma of the kidney, also known as papillary renal cell carcinoma (PRCC), is the second most common subtype of renal cell carcinoma (RCC), accounting for about 10-15% of all kidney cancers. It originates in the tubules of the kidney and is characterized by the formation of small, finger-like projections called papillae. PRCC is further classified into two types: Type 1, which tends to have a better prognosis, and Type 2, which is more aggressive and may have a poorer outcome.
Symptoms
Symptoms of papillary carcinoma of the kidney may not be apparent in the early stages. As the disease progresses, symptoms can include:
- Blood in the urine (hematuria)
- Persistent pain in the side (flank pain)
- A mass or lump in the side or abdomen
- Unexplained weight loss
- Fever
- Fatigue
- High blood pressure (hypertension)
Disease Aetiology (Causes)
The exact cause of papillary carcinoma of the kidney is not fully understood, but several risk factors have been identified, including:
- Smoking
- Obesity
- High blood pressure
- Long-term dialysis
- Genetic factors, such as inherited conditions like hereditary papillary renal cell carcinoma
Diagnosis
Diagnosing papillary carcinoma of the kidney typically involves a combination of:
- Imaging tests, such as ultrasound, computed tomography (CT) scans, and magnetic resonance imaging (MRI), to visualize the kidneys and any abnormalities.
- Urine tests to check for blood or other signs of kidney problems.
- Blood tests to assess kidney function.
- Biopsy, where a sample of kidney tissue is taken and examined under a microscope for cancer cells.
Treatment
Treatment for papillary carcinoma of the kidney depends on the stage of the disease, the patient’s overall health, and other factors. Options may include:
- Surgery to remove the tumour or the entire kidney (nephrectomy), which is the most common treatment.
- Targeted therapy, which uses drugs to target specific genetic and molecular changes that are found in some types of kidney cancer.
- Immunotherapy, which helps to boost the body’s natural defenses to fight the cancer.
- Radiation therapy and chemotherapy are less commonly used but may be recommended in certain situations.
What support can we give for the Papillary Carcinoma of the Kidney?
Papillary Carcinoma of the Kidney is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Papillary Carcinoma of the Kidney, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
