What is Nodular Sclerosis Hodgkin’s Lymphoma?
Nodular sclerosis Hodgkin’s lymphoma is a subtype of leukocyte cancer (white blood cells cancer) that is characterized by the presence of collagen fibers surrounding Hodgkin-Reed-Sternberg cells in the lymph nodes on histological examination of tissue biopsy (observation under a microscope). The most common sites for the development of nodular sclerosis classical Hodgkin’s lymphoma are cervical lymph nodes (lymph nodes of the neck), lymph nodes of the mediastinum ( chest cavity lymph nodes), liver, spleen, lungs, bones, and bone marrow.Disease Etiology (Causes)
There is no well-known cause, but there has been an association between the development of classic Hodgkin’s lymphoma of nodular sclerosis and previous or ongoing Epstein-bar virus (EBV) infection.Disease Epidemiology
It accounts for approximately 70% of all classic Hodgkin’s lymphomas. This is more common in the upper socio-economic class group. It is equally common in both men and women. The average age at onset of the disease ranges from 15 to 34 years.Signs and Symptoms
The Nodular sclerosis classical Hodgkin’s lymphoma presents with the general symptoms of cancer. These are- Fever
- Night sweats
- Weight loss
- Constant Tiredness
Diagnosis
The following are the diagnostic tests that help diagnose the lymphocyte depleted classical Hodgkin’s lymphoma.- Complete blood count (CBC) with peripheral smear
- Blood coagulation profile
- Bone marrow aspiration and cytology
- Immunohistochemistry
- EBV antibodies test
- CT- scan, MRI, PET scan, Ultrasonography (USG), and X-Ray to detect the site and extent of cancer.
Treatment
The most commonly practised and effective treatment therapy in the case of nodular sclerosis Hodgkin’s lymphoma is chemotherapy alone or chemotherapy with radiotherapy.What Support can we Give for Nodular Sclerosis Classical Hodgkin’s Lymphoma?
Nodular Sclerosis Classical Hodgkin’s Lymphoma is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Nodular Sclerosis Classical Hodgkin’s Lymphoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
