What is Malignant Rhabdoid Tumour?
Malignant rhabdoid tumour is a highly aggressive and rare form of cancer predominantly found in infants and young children. Although initially identified in the kidneys (where it was termed rhabdoid tumour of the kidney), it can also occur in other soft tissues and organs throughout the body. This type of cancer is characterized by its rapid growth and tendency to spread to other parts of the body (metastasize).
Symptoms
The symptoms of malignant rhabdoid tumour can vary significantly depending on the location of the tumour. They may include:
- A palpable mass or swelling in the affected area.
- Pain or discomfort in the area of the tumour.
- Symptoms related to the compression of organs or tissues, such as difficulty breathing if the tumour is in the chest.
- General symptoms like fatigue, fever, or weight loss.
Disease Aetiology (Causes)
The exact cause of malignant rhabdoid tumours is not completely understood. However, most cases are associated with mutations in the SMARCB1 gene. These mutations appear to be sporadic, occurring without a known cause, rather than being inherited.
Diagnosis
Diagnosing a malignant rhabdoid tumour involves:
- Imaging Studies: MRI, CT scans, and ultrasound are used to identify the presence and extent of the tumour.
- Biopsy: A sample of the tumour tissue is examined under a microscope to confirm the diagnosis.
- Genetic Testing: May be performed to detect SMARCB1 gene mutations.
Treatment
The treatment for malignant rhabdoid tumour typically includes a combination of:
- Surgery: To remove the tumour, when possible.
- Chemotherapy: Often the primary treatment due to the aggressive nature of the tumour.
- Radiation Therapy: Used in some cases, especially if the tumour cannot be completely removed surgically.
- Targeted Therapy and Immunotherapy: Emerging treatment options being explored in clinical trials.
What support can we give for Malignant Rhabdoid Tumour?
Malignant Rhabdoid Tumour is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Malignant Rhabdoid Tumour, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
