What is Large Cell Lung Carcinoma?
Large cell lung carcinoma is a type of lung cancer that originates from the outer regions of the lungs. Large cell lung carcinoma is an aggressive tumour that grows rapidly and has the tendency to spread to other parts of the body. Large cell lung carcinoma is a subtype of non-small cell lung carcinoma and accounts for approximately 80-85% of all lung cancers.
Disease Causes
There is no well-known cause. However, there is a strong link between the presence or diagnosis of large cell lung cancer and chronic tobacco smoking. Other risk factors for developing large cell lung cancer are a working history in uranium mines and long-term exposure to radon gas.
Signs and Symptoms
Signs and symptoms depend on the extent and spread of the disease to other organs or parts of the body. If the cancer is limited to the lungs, the patient will only experience signs and symptoms of the respiratory system. At the same time, in cases where this cancer spreads to other parts of the body, the patient also experiences B symptoms of cancer. General respiratory symptoms of large cell lung carcinoma
- Persistent cough
- Dyspnea (shortness of breath or difficulty in breathing)
- Chest pain that worsens with coughing, laughing and breathing deeply
- Coughing up blood
- Wheezing without having an asthma history
- Clubbing of the fingers and nails (A physical sign characterized by a bulging extension at the ends of one or more fingers or toes).
The following are the general B symptoms (systemic symptoms) of large cell lung cancer when it spreads to other organs of the body. These are
- Fever
- Fatigue
- Night sweats
- Weight loss
- Bone pains
Diagnosis The following diagnostic tests and procedures can be used to make a diagnosis. These are;
- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumour.
- Tumour biopsy ( lung tumour biopsy to remove a small sample of lung tissue for histopathological examination)
- Sputum cytology
- USG-guided fine needle aspiration cytology
Treatment options include surgical resection of the tumour, Chemotherapy, Radiotherapy, targeted therapy, and immunotherapy. Surgery is the main option, all patients with stage-I lung cancer should undergo surgical resection of the tumour (complete removal of the tumour along with the removal of some surrounding healthy tissues). Chemotherapy and radiotherapy should be considered in advanced cases of cancer.
What support can we give for Large Cell Lung Carcinoma?
Large Cell Lung Carcinoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Large Cell Lung Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
