What is Intravascular Large B-Cell Lymphoma?
It is a rare abnormal growth of B-lymphocytes in small capillaries, arteries, and veins. B-lymphocytes are white blood cells responsible for the production of antibodies. Antibodies are proteins that are produced by our body’s immune system and help it fight infectious agents. Large intravascular B-cell lymphomas are malignant. A malignant tumour is a tumour that can invade local tissues and spread to distant parts of the body. The most common sites for the development of intravascular large B cell lymphomas are skin, nerves, bones, lungs, and other body organs.
Disease Etiology (Cause)
Intravascular large B cell lymphoma has no known cause.
Signs and Symptoms
Signs and symptoms vary and depend upon the involvement of the site, systems, or organ of the body. Signs and symptoms associated with intravascular large B cell lymphoma of the Central Nervous System (nerves, brain, and spinal cord). These are;
- Disturbed or altered mental status
- Loss of memory, forgetfulness
- Seizures or fits
- Burning, pricking or numbness sensation in hands, arms, legs, and feet
- Difficulty in speaking
- Bone pains
Signs and symptoms associated with intravascular large B cell lymphoma of lungs. These are
- Shortness of breath, difficulty in breathing
- Persistent cough
- Coughing up blood
General or B symptoms associated with intravascular large B cell lymphoma. These are
- Unexplained weight loss
- Night sweats
- Bone pains
The following diagnostic tests and procedures can be used to make a diagnosis. These are
- Imaging techniques like X-ray, USG (ultrasonography), MRI, CT-Scan, and PET –scan to detect the size and extent of the tumour.
- Tumour biopsy and histopathological examination
Treatment options are radiation therapy and chemotherapy.
What Support can we Give for Intravascular Large B-Cell Lymphoma?
Intravascular Large B-Cell Lymphoma is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Intravascular Large B-Cell Lymphoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.