What is an Insulinoma Tumour of the Pancreas?Insulinoma is a tumour of pancreatic cells that develops as a result of excessive secretion or proliferation of cells that secrete the hormone insulin. These tumours secrete excess amounts of insulin, more than the body needs. The excessive production of insulin causes low blood sugar levels to result in rapid heartbeat, mental confusion, weakness, and sweating. Pancreatic insulinoma is not cancerous and does not spread to nearby or distant parts of the body. A normal blood level of Insulin is responsible for controlling blood sugar levels.
Disease CausesThere is no well-known cause of insulinoma pancreas however certain hereditary and genetic mutations (such as multiple endocrine neoplasia types 1, neurofibromatosis type 1, and Von-Hippel-Lindau syndrome) are considered responsible for the development of insulinoma pancreas.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Recurrent very low blood sugar levels
- Rapid heartbeat
- Low blood pressure
- Mental confusion
- Excessive hunger
- Pain in the abdomen
- Flatulence or gas in the abdomen
- Pain in the back
- A lump or mass in the abdomen
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis; these are
- Imaging techniques like CT-scan, MRCP (magnetic resonance cholangiopancreatography), MRI, TUS (transcutaneous ultrasonography), and PET-scan.
- Endoscopic USG
- CBC ( complete blood count)
- BSR( Blood sugar random), Fasting blood sugar, and GTT ( glucose tolerance test)
- Blood tests for serum insulin levels
- Histopathological examination of the pancreatic cell’s tumour