Colonic Goblet Cell Carcinoid
What is Goblet Cell Carcinoid Tumour of the Colon?
Goblet carcinoid tumour of the colon is a rare type of cancer that arises from epithelial cells that form hormone-secreting glands and nerve cells in the body, and thus they are of neuroendocrine origin. Goblet cell carcinoid tumour usually arises from neuroendocrine cells of the stomach, duodenum, small intestine, colon and rectum. Goblet cell carcinoid tumour of the colon shows poor prognosis (likely course of the disease) with a 5-year survival rate ranging from 73%-84%.
There is no well-known cause, however, certain hereditary and genetic mutations are considered responsible for the development of goblet cell carcinoid tumours of the colon.
Signs and Symptoms
Goblet cell carcinoid tumor of the colon is usually asymptomatic but may present with the following signs and symptoms. These are
- Melena ( black colour stool due to bleeding from the upper gastrointestinal tract)
- Malaise, fatigue, and difficulty in breathing while walking or doing any physical activity due to loss of blood from the ulcerated site of the tumour.
- Abdominal pain
- Loss of appetite
- Loss of body weight
- Feeling of fullness even after a few mouthfuls
Diagnosis and Treatment
A diagnosis can be made through by
- Complete blood count (CBC)
- Blood coagulation profile
- BUN ( blood urea and nitrogen)
- Serum creatinine
- Liver function tests LFTs
- Amylase and lipase values
- Imaging techniques like CT-scan, MRI, PET-scan, X-Ray, and USG to detect the site and size of the tumour.
- Preoperative biopsy
Other Options for Treatment
Surgical resection (removal or cutting of the diseased part through surgery) is the most common and effective treatment option.
What Support can we Give for Colonic Goblet Cell Carcinoid?
Colonic Goblet Cell Carcinoid is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Colonic Goblet Cell Carcinoid, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
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