What Is Gallbladder Adenocarcinoma?
Gallbladder adenocarcinoma is the most common type of gallbladder cancer, originating in the glandular cells that line the inside surface of the gallbladder. Part of the biliary tree, the gallbladder is a small organ beneath the liver that stores bile, a fluid produced by the liver to digest fats. Adenocarcinoma accounts for the vast majority of gallbladder cancers and is known for its aggressive nature and poor prognosis if not detected early.
Symptoms
Early stages of gallbladder adenocarcinoma often present no symptoms, making early detection difficult. As the cancer progresses, symptoms may include:
- Jaundice (yellowing of the skin and eyes)
- Abdominal pain, especially in the upper right quadrant
- Nausea and vomiting
- Unintended weight loss
- Bloating
- Fever
Disease Aetiology (Causes)
While the exact cause of gallbladder adenocarcinoma is unknown, several risk factors have been identified:
- Gallstones and chronic gallbladder inflammation are significant risk factors.
- A history of gallbladder polyps
- Obesity
- Gender, with women being more likely to develop this cancer than men
- Age, as the risk increases with age
- Certain inherited conditions and ethnic backgrounds
Diagnosis
Diagnosing gallbladder adenocarcinoma typically involves a combination of methods:
- Imaging tests, such as ultrasound, CT scans, and MRI, to visualize the gallbladder and identify abnormalities.
- Endoscopic ultrasound (EUS) to get detailed images and possibly perform a biopsy.
- Blood tests to look for markers that might indicate cancer.
- A biopsy, where a small sample of tissue is removed and examined under a microscope, is the definitive method for diagnosing cancer.
Treatment
Treatment options for gallbladder adenocarcinoma depend on the stage of the cancer and may include:
- Surgery is the primary treatment for early-stage cancer and may involve removing the gallbladder (cholecystectomy), parts of the liver, and nearby lymph nodes.
- Chemotherapy and radiation therapy may be used as adjunctive treatments to surgery, for palliative care, or when the cancer is inoperable.
- Targeted therapy and immunotherapy are being explored in clinical trials and may be options based on specific genetic markers of the cancer.
What support can we give for the Gallbladder Adenocarcinoma?
Gallbladder Adenocarcinoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Gallbladder Adenocarcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
