What is Extra Skeletal Ewing Sarcoma?Extraskeletal Ewing’s sarcoma is a rare, cancerous growth of rapidly multiplying nature that develops in the soft tissues instead of bones. It is high a grade tumor with poor differentiation from other soft tissue tumors. High-grade tumors are those who tend to grow and spread more quickly than low-grade tumors. Most frequently, they are developed from the soft tissues of the chest wall (ribs and shoulder blades), paravertebral region (anterior, posterior and lateral region of the vertebral column), abdomen, pelvis, gluteal region (buttocks), and lower extremities (part of the body from the hip to the toe).
Disease EpidemiologyIt is more common in children and teenagers. The annual incidence rate of extraskeletal Ewing sarcoma is about 1-3 cases per 1 million population. It is more common in males as compared to females.
Disease EtiologyExtraskeletal Ewing sarcoma (ESES) has no clear, exact known cause. Some genetic mutations in chromosome number 22 and 11 are considered responsible for the development of ESES.
Signs and SymptomsThe patient can present with the following signs and symptoms. These are:
- A large and palpable mass.
- A mass or lump that is usually painless, it is painful only in 30% cases.
- A mass or lump most commonly present in the soft tissues of the thorax and lower extremities.
- Night sweats
- Weight loss
Diagnosis and TreatmentFollowing diagnostic tests and procedures can be used to make a diagnosis. These are:
- Radiological and imaging techniques like CT-scan, PET-scan, MRI, and X-ray.
- FNAC (fine needle aspiration cytology)
- Tumor Biopsy