What is Endometrial Stromal Sarcoma of the Uterus?Endometrial stromal sarcoma is a rare type of cancer that arises from the endometrial stromal tissues of the uterus, connective tissues, or smooth muscle cells and often affects women between the ages of 40-50.
Disease CausesThere is no well-known cause, however, certain hereditary and genetic mutations are considered responsible for the development of endometrial stromal sarcoma.
Signs and symptomsIn the early stages of a germ cell tumor of the ovary, the patient does not show any signs and symptoms, as the tumor progresses, the patient may suffer from the following signs and symptoms. These are
- A mass or lump in the abdomen
- Pain in the abdomen in a few cases
- Bleeding from the vagina between menstrual cycles and after menopause (permanent cessation of menstruation after the age of 49 years).
- Frequent urge to go to toilet for urination (Frequent urination)
DiagnosisFollowing diagnostic tests and procedures can be used to make the diagnosis. These are
- Complete blood count ( CBC)
- Serum tumor markers
- Imaging techniques like ultrasonography (USG), CT-scan, MRI, and X-Ray to detect the site, size, and extent of the tumor.
- Pelvic examination through per-speculum examination of the vagina, cervix, and ovaries. A speculum is a gynecological instrument used to visualize the vaginal wall, cervix, uterus, and ovaries to detect any abnormality.
- Dilatation and curettage for diagnosis
- Serum B-HCG levels
- Alpha-fetoprotein levels (AFP)