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Endometrial Stromal Sarcoma of the Uterus – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | May 30, 2023

What is Endometrial Stromal Sarcoma of the Uterus?

Endometrial stromal sarcoma of the uterus is a rare type of uterine cancer that begins in the stromal cells, which make up the supportive framework (stroma) of the uterus. ESS accounts for a small percentage of uterine cancers. It is generally slow-growing, but it has the potential to spread to other parts of the body over time.

Symptoms

Symptoms of Endometrial stromal sarcoma of the uterus may include:
  • Unusual vaginal bleeding or discharge
  • Pelvic pain or discomfort
  • A palpable mass or lump in the pelvic area
  • Unexplained weight loss
  • Frequent urination due to pressure on the bladder

Disease Aetiology (Causes)

The exact cause of endometrial stromal sarcoma of the uterus is unknown, but it is likely to involve genetic mutations that lead to uncontrolled cell growth and division. Certain inherited genetic syndromes may increase the risk, although most cases of endometrial stromal sarcoma of the uterus occur in the absence of a clear genetic predisposition.

Diagnosis

The diagnosis of endometrial stromal sarcoma of the uterus often involves:
  • Detailed medical history and physical examination
  • Endometrial biopsy or dilation and curettage (D&C) to obtain tissue for examination under a microscope
  • Imaging tests such as ultrasound, CT scan, or MRI to ascertain the size, location, and extent of the tumour

Treatment

The treatment for endometrial stromal sarcoma of the uterus of the uterus typically involves:
  • Surgery: The primary treatment, involves the surgical removal of the uterus (hysterectomy), along with the fallopian tubes and ovaries.
  • Hormone Therapy: This involves the use of drugs to block hormone receptors in cancer cells, thereby slowing the growth of the cancer.
  • Radiation Therapy and Chemotherapy: These may be considered in some cases, particularly for more advanced diseases or if the cancer recurs.

What Support can we Give for Endometrial Stromal Sarcoma of the Uterus?

Endometrial Stromal Sarcoma of the Uterus is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as the Endometrial Stromal Sarcoma of the Uterus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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