Disease EpidemiologyEmbryonal Rhabdomyosarcoma (ERM) is an uncommon cancer that mostly affects the population under the age of 15. Most of the cases are diagnosed after the 15th day of birth and before the age of 15. It is observed that male babies are affected more than females babies.
Disease EtiologyThe exact cause of the Embryonal Rhabdomyosarcoma(ERM) is unknown. However, studies have suggested that certain medical conditions can be the cause of this cancer which are: Fraumeni syndrome: a rare genetic problem that makes an infant develops cancer at a certain time of his/her life. Beckwith-Wiedemann syndrome: a by-birth genetic problem that can cause excessive growth of the body parts, including the internal organs of the body. Costello syndrome & Noonan syndrome: these cause deformities, developmental delays (word Syndrome stands for a condition in which a group of symptoms is found together).
Signs and SymptomsSign and symptoms of Embryonal Rhabdomyosarcoma (ERM) depend on the size and location of cancer. The symptoms which are most noted are;
- A painless lump in the child body which is usually palpable
- Eye bulging
- Swollen eyelid
- Difficulty in passing urine and stool
- Sometimes blood in urine and stools
- Numbness and weakness of muscles if the lump is pressing nerves of extremities.
Diagnosis and TreatmentFollowing diagnostic tests and procedures can be used to make a diagnosis. These are:
- Radiological and imaging techniques like CT-scan, PET-scan, MRI, and X-ray.
- FNAC (fine needle aspiration cytology)
- Tumor Biopsy
- Surgical removal of the tumor or cancerous growth
- Radiation Therapy