What is Clear Cell Adenocarcinoma of the Vagina?
Clear cell adenocarcinoma of the vagina is a rare type of cancer that originates from the uncontrolled division of epithelial tissues of the vagina as a result of side effects of a drug named Diethylstilbestrol (DES) which is usually recommended in high-risk pregnancy to avoid miscarriage. The epithelial tissues of the vagina make up the internal lining of the vagina.
Causes
Of all vaginal malignancies, clear cell adenocarcinoma accounts for only 10% of cases. It is exceedingly uncommon. Diethylstilbestrol (DES), a medication used during pregnancy, is the primary source of the problem.
However, there is another type of vaginal clear cell adenocarcinoma that is not related to DES. This is known as primary clear cell carcinoma of the vagina associated with non-diethylstilbestrol. The cause of this type of cancer is unknown.
Signs and symptoms
The patient may suffer from the following signs and symptoms:
- Abnormal bleeding from the vagina
- Abnormal vaginal discharge that may be watery, pink, or foul-smelling.
- Pain during sexual intercourse
- Pelvic pain or discomfort
- A palpable mass or lump in the vaginal area
Diagnosis
The following diagnostic tests and procedures can be used to make a diagnosis:
- Complete physical pelvic examination
- Trans-vaginal ultrasound
- Computed tomography (CT-pelvis)
- Biopsy of the lesion/tumour and histo-pathological examination
Treatment
Surgical excision is the primary treatment for vaginal tumours. Chemotherapy and radiation therapy are other choices. Surgery to remove the affected region of the vagina is usually enough to treat less aggressive, low-grade cancers. Treatment for vaginal high-grade clear cell adenocarcinoma usually consists of surgery and chemotherapy. In all cases of clear cell adenocarcinoma of the vagina, strict monitoring of the patient is required.
What support can we give for the Clear cell adenocarcinoma of the vagina?
Clear cell adenocarcinoma of the vagina is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Clear cell adenocarcinoma of the vagina, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.