What is Classical Hodgkin Lymphoma?Classic Hodgkin’s lymphoma is a special type of white blood cell cancer that arises from abnormal B lymphocytes. These abnormal B cells are known as Sternberg’s reed cells. It can develop at any age, but the average age for development of classic Hodgkin’s lymphoma ranges from 20-40 years, with the peak incidence over the age of 55.
What is Lymphoma?Lymphoma is a cancer of the white blood cells that have developed due to the uncontrolled division of lymphocytes (white blood cells).
What is B-lymphocyte?B-lymphocyte is a type of white blood cell that fights off pathogens and foreign substances by producing antibodies against these pathogens or substances.
Disease EtiologyThere is no well-known cause, but certain infections such as Epstein Bar Virus (EBV) infection and HIV (Human immune deficiency virus) infection, previous radiation exposure, or certain harmful chemicals are risk factors for developing follicular lymphoma.
Signs and symptomsThe patient may suffer from the following signs and symptoms. These are
- Night sweats
- Weight loss
- Enlarged or swollen painless slowly growing lymph nodes in the neck armpit, abdomen, and groin
- Shortness of breath where the tumor is spread to the lungs
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis. These are
- Imaging studies such as X-ray, CT-scan, and MRI to detect the site, size, and extent of the metastasis (spread of the tumor)
- CT chest, the scan of bones, and PET-Scan to assess the areas and spread of the tumor
- Lymph node biopsy / Tumor biopsy
- Bone marrow biopsy