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Basal Cell Carcinoma of the Anus

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Posted by Matthew O’Connor | Feb 3, 2024

What Is Basal Cell Carcinoma of the Anus?

Basal Cell Carcinoma of the Anus is a type of skin cancer that is most commonly associated with areas of the body exposed to the sun, making it an unusual occurrence in the anal region. BCC of the anus is extremely rare, given the typical growth pattern and locations of basal cell carcinomas. This form of cancer arises from the basal cells, which are found in the deepest layer of the epidermis and around hair follicles. Despite its rarity in the anal area, it is important to recognize and treat it appropriately, as BCC can be locally invasive.

Symptoms

Symptoms of basal cell carcinoma of the anus may include:

  • A persistent, non-healing sore or growth in the anal area
  • Bleeding from the growth or sore
  • Discomfort or pain in the anal region
  • Itchiness or irritation around the anus
  • A change in bowel habits or the sensation of an obstruction could be a sign if the carcinoma is large or invasive

Disease Aetiology (Causes)

The exact cause of basal cell carcinoma in the anus is unclear, as the typical risk factors for BCC (such as sun exposure) are not relevant to this region. Genetic predispositions, chronic irritation, or immunosuppression could potentially play a role.

Diagnosis

Diagnosing basal cell carcinoma of the anus involves:

  • Physical examination to assess the appearance and characteristics of the lesion.
  • Biopsy, where a sample of the suspicious tissue is taken and examined under a microscope to confirm the presence of cancer cells.
  • Imaging tests, such as MRI or CT scans, might be used to assess the extent of the cancer if it is suspected to have invaded deeper tissues.

Treatment

Treatment options for basal cell carcinoma of the anus include:

  • Surgical excision to remove the tumour along with some surrounding healthy tissue to ensure clear margins.
  • Mohs micrographic surgery, a procedure that removes the cancer layer by layer and examines each layer under a microscope until no abnormal cells remain. This method is highly effective but less commonly used in the anal region.
  • Radiation therapy may be considered for tumours that are not amenable to surgery or for patients who are not surgical candidates.
  • Topical treatments or less commonly used methods may be considered for very superficial lesions, but their effectiveness in the anal region may be limited.

What support can we give for the Basal Cell Carcinoma of the Anus?

Basal Cell Carcinoma of the Anus is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Basal Cell Carcinoma of the Anus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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