What is Angioimmunoblastic T-cell Lymphoma?
Angioimmunoblastic T-cell Lymphoma is a type of white blood cell cancer that originates from the uncontrolled division or multiplication of the T-lymphocytes. T-cells, or T lymphocytes, are the main components of the body’s immune system that helps to fight infections.
Disease Epidemiology
It accounts for one to two percent of all white blood cell cancers. It is more common in older people.
Disease Causes
There is no well-known cause, however, it is believed that overactive or malfunctioning of the immune system is the likely cause of the development of angioimmunoblastic T-cell lymphoma.
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- High-grade fever
- Excessive sweating at the night
- Unexplained weight loss
- Rashes on the skin
- Enlargement of multiple lymph nodes of the body
- Itching
- Constant fatigue
At the advanced stages of the disease, the patient may suffer from
- The difficulty in breathing
- Enlargement of the liver
- Due to the frequent involvement of bone marrow patients may also present with the symptoms of anemia (decreased RBCs count or decreased oxygen-carrying capacity of the blood), lethargy, difficulty in breathing, and weakness.
- Thrombocytopenia: decreased platelet leading to a tendency to bleeding and bruising on the skin.
Diagnosis
The following diagnostic techniques and procedures can be used to make a diagnosis these are
- Complete blood count (CBC)
- LFT’s (Liver function test)
- Renal function tests
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumour.
- Lumbar puncture Test
- Tumour biopsy and histopathology
Treatment
Surgical resection of the tumour (surgical removal of the tumour), chemotherapy, radiation therapy, and stem cell transplantation are the main treatment options.
What Support can we Give for Angioimmunoblastic T-cell Lymphoma?
Angioimmunoblastic T-cell Lymphoma is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Angioimmunoblastic T-cell Lymphoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
