What is Angiomatoid Fibrous Histiocytoma?Angiomatoid fibrous histiocytoma is a rare soft tissue tumour that commonly occurs in children and young adults. It is uncommon in older people. It is a low-grade tumour that grows slowly and rarely metastasizes to other distant parts of the body. It usually develops into the arms, legs, or neck in rare cancer it can also originate from the lungs, abdomen, ovaries, and female’s external genitalia.
Disease EpidemiologyIt is a rare tumour. This usually occurs in children and young adults and less commonly in older people. The peak age of onset is 30 years.
Disease CausesThere is no well-known cause, however, certain genetic mutations (faulty alterations in the genes) are considered responsible for the development of angiomatoid fibrous histiocytoma.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- The tumour usually develop on the arms, legs, or neck
- The tumour may be painless or painful
- Constant Tiredness
- Loss of appetite
- Excessive amounts of myeloma protein
- Difficulty in breathing
- Paleness of the skin due to decreased red blood cell count
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis these are
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumour.
- Tumour biopsy and histopathology