Without a Ribbon
  • Home
  • About
    • Events
    • Get In Touch
  • Rare Cancer Resources
  • Shop
  • How You Can Help
  • Meet Warriors
  • News
  • Login
  • Register

Select Page

HELP

LEARN

EVENTS

Alpha Heavy Chain Disease – Symptoms, Treatment & Support

Become part of our growing rare cancer community.
Join our Facebook support group

Join Now

Posted by adeel | Mar 21, 2021

What is an Alpha Heavy Chain Disease?

Alpha heavy chain disease is a plasma cell cancer characterized by incomplete production of antibodies with overproduction of heavy chains without associated light chains. The clinical characteristics of the disease are diarrhoea and malabsorption.

What are Antibodies and Their Structure?

An antibody is a large Y-shaped protein that is produced by the immune system of the body in response to the entry of certain foreign disease-causing objects such as viruses, bacteria, or any other microorganisms in the body. These antibodies fight against these foreign disease-causing agents and neutralize them. The antibody is a Y-shaped structure and consists of two-light and two-heavy polypeptide chains. Polypeptide chains are consisting of several amino acids. An amino acid is a basic building unit of protein.

Disease Etiology (Causes)

There is no exact-well-known cause, however, there is an association between the alpha-HCD and immunoproliferative small intestinal disease.

Disease Epidemiology

It is distributed in the countries of North Africa and the Middle East / Mediterranean. It is also common in populations with poor sanitation. It is a rare disease, with 400 cases reported worldwide to date. It usually affects young people, whose average age ranges from 20-30 years.

Signs and Symptoms

The patient may suffer from the following signs and symptoms. These are

  • Abdominal Pain or discomfort
  • Diarrhea
  • Weight loss
  • Intestinal worm infestation

Diagnosis

The following diagnostic techniques and procedures can be used to make a diagnosis. These are

  • Serum test for the detection of antibodies
  • UCE (urine complete examination)
  • Stool analysis

Treatment

Prescribing drugs such as anthelmintics and antibiotics to kill worms, bacteria, and viruses is the initial treatment. In advanced cases, chemotherapy and surgical resection (surgical removal of a tumor or part of the disease along with some healthy surrounding tissue and reuniting the rest of the organ to preserve its function) of the tumor (s) are treatment options.


 

What Support can we Give for Alpha Heavy Chain Disease?

Alpha Heavy Chain Disease is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Alpha Heavy Chain Disease we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

Sign Up

You can help us with your donation:

Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:

Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
Sponsorship — If you wish to sponsor our charity, please contact us using this form.
Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

Share:

PreviousMalignant Hemangiopericytoma or Solitary Fibrous Tumor – Symptoms, Treatment & Support
NextAlveolar Soft part Sarcoma – Symptoms, Treatment & Support

What We Do

Without a Ribbon

Without a Ribbon is an Australian organisation that provides support and resources for sufferers of rare cancer.

We provide a designated platform for Warriors to obtain information specific to their Rare Cancer, as well as offer costing-saving opportunities through links with Australia Businesses.

Learn More

Do You Suffer From a Rare Cancer?

Without a Ribbon provides Warriors with the support, platform and resources needed to aid them in their journey. Our community is always open to new Warriors.

  • Become a Warrior
  • Join our Facebook Support Group

How Can You Help?

Our goal is to provide support for sufferers of rare cancers and raise awareness for their conditions. Your support helps us to achieve this.

  • Make a Donation
  • Become a Sponsor
  • Volunteer with Us

If you need any help or advice just

Get In Touch

© Without a Ribbon 2019. All rights reserved.Powered by WEB 105 Creative

Stay up to date.

Sign up to our newsletter