What is Testicular Monophasic Choriocarcinoma?Testicular Monophasic choriocarcinoma is a rare type of tumour that arises from the testes and consists of predominant intermediate trophoblastic cells; these trophoblastic cells are usually similar to the trophoblastic cells placental site trophoblastic tumour of the uterus.
What is Choriocarcinoma?A particular kind of cancer that arises from trophoblastic cells is called choriocarcinoma. Trophoblastic cells are the cells that make up the placenta and aid in the embryo’s attachment to the uterus through the placenta to get blood and nutrition from the mother. If these trophoblastic cells are still present after delivery, choriocarcinoma can form. Similar cells can be seen in monophasic testicular choriocarcinoma.
Disease CausesMonophasic choriocarcinoma of the testes is a germ cell tumour that develops in the testes. Although the exact cause is unknown, some hereditary and genetic alterations are thought to play a role in the tumour’s development.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- A palpable (able to be touched or felt) mass in the scrotum
- Swelling of the scrotum
- Pain in the testes that can radiate (move) to the groin or abdomen
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are
- A physical examination of the pelvic area (hip) to see unusual changes in the scrotum, to asses any mass or lump in this area
- Imaging tests like scrotal ultrasonography (USG), CT-scan testis, CT-scan abdomen, CT scan chest, and brain to detect the tumour size, site and metastasis.
- Tumour Biopsy
- Blood tests to check Serum B-HCG level