What Is Renal Cell Carcinoma – Chromophobe?
Renal cell carcinoma – chromophobe (ChRCC) is a distinct subtype of renal cell carcinoma that accounts for approximately 5% of all kidney cancers. Characterized by cells that appear pale or clear under the microscope due to their high lipid content, chromophobe RCC typically has a better prognosis than other types of RCC. It originates from the kidney’s cortical cells, which are involved in the organ’s filtering and urine production processes.
Symptoms
In the early stages, chromophobe renal cell carcinoma may not cause any symptoms. As the disease progresses, symptoms may include:
- Blood in the urine (hematuria)
- A lump or mass in the side or abdomen
- Persistent pain in the side
- Unexplained weight loss
- Fever
- Fatigue
- High blood pressure (less common)
Disease Aetiology (Causes)
The exact cause of chromophobe renal cell carcinoma is not known. However, certain genetic and environmental factors may increase the risk, including:
- Smoking
- Obesity
- High blood pressure
- Family history of kidney cancer
- Certain inherited syndromes, such as Birt-Hogg-Dubé syndrome, may be associated with a higher risk of developing ChRCC.
Diagnosis
Diagnosis of chromophobe renal cell carcinoma typically involves:
- Imaging tests such as ultrasound, computed tomography (CT) scans, and magnetic resonance imaging (MRI) to identify abnormalities in the kidney.
- Blood and urine tests to assess kidney function and look for signs of cancer.
- A biopsy, where a sample of kidney tissue is removed and examined under a microscope to determine the type of cells and the presence of cancer.
Treatment
Treatment options for chromophobe renal cell carcinoma depend on the stage of the disease, the overall health of the patient, and other factors. They may include:
- Surgery, which is the primary treatment and involves removing the tumour or the entire kidney (nephrectomy).
- Active surveillance for small, localized tumours that are not causing symptoms.
- Targeted therapy and immunotherapy, which are more commonly used for advanced or metastatic disease.
- Radiation therapy and chemotherapy are generally less effective for kidney cancer but may be considered in specific situations.
What support can we give for the Renal Cell Carcinoma?
Renal Cell Carcinoma is a rare cancer, meaning it is not as well-known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Renal Cell Carcinoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:
