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Papillary Serous Carcinoma of the Uterus – Symptoms, Treatment & Support

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Posted by Matthew O’Connor | May 30, 2023

What is Papillary Serous Carcinoma of the Uterus?

Papillary serous carcinoma of the uterus, also known as uterine papillary serous carcinoma, is an aggressive subtype of endometrial cancer. It accounts for a small percentage of all endometrial cancers but is responsible for a significant number of deaths due to its tendency to spread early. Despite its rarity, it is crucial to diagnose and treat papillary serous carcinoma of the uterus early due to its aggressive nature.  

Disease Aetiology (Causes)

The exact cause of papillary serous carcinoma of the uterus is unknown, but it is believed to involve genetic mutations that lead to the uncontrolled growth and division of cells. Unlike most types of endometrial cancer, Papillary serous carcinoma of the uterus does not appear to be linked to an excess of estrogen. Some studies suggest a possible link between Papillary serous carcinoma of the uterus and a history of breast cancer or ovarian cancer.  

Diagnosis

Diagnosis of papillary serous carcinoma of the uterus often involves:

  • Detailed medical history and physical examination
  • Endometrial biopsy or dilation and curettage (D&C) to obtain tissue for examination under a microscope
  • Imaging tests such as ultrasound, CT scan, or MRI to ascertain the size, location, and extent of the tumour

Treatment

The treatment for papillary serous carcinoma of the uterus typically involves a combination of strategies:

  • Surgery: The primary treatment involves surgical removal of the uterus (hysterectomy), along with the fallopian tubes and ovaries. Depending on the extent of the disease, nearby lymph nodes may also be removed.
  • Radiation Therapy: This can be used before surgery to shrink the tumour, or after surgery to kill any remaining cancer cells.
  • Chemotherapy: Can be used in combination with surgery and radiation therapy, particularly in more advanced cases or if the cancer recurs.

 


What Support can we Give for Papillary Serous Carcinoma of the Uterus?

Papillary Serous Carcinoma of the Uterus is rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. So, we provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from rare cancer such as Papillary Serous Carcinoma of the Uterus, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!

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Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways:

Donations — Without a Ribbon are grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences.
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Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.

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