What is a Non-Seminomatous Germ Cell Tumour of the Testis?Non-seminomatous germ cell tumour of the testicles is a type of testicular cancer that usually occurs in men between the ages of 15 and 30 and arises from the sperm-producing cells in the testes. However, the average age of development of a non-seminomatous germ cell tumour is 25 years. It is an aggressive type of tumour, aggressive tumours are tumours that grow rapidly and spread to other parts of the body.
What is Testis?The testicles are the male sex glands in the human body, there are a pair of testes in the human body. The function of the testis is to produce sperm and male hormones for reproduction.
Disease Etiology (Causes)The testicles or testes are the male sex glands in the human body, there are a pair of testes in the human body. The function of the testis is to produce sperm and male hormones for reproduction. Certain genetic mutations, a family history of germ cell tumours, undescended testes (in the case of an undescended testicle, the testicle does not move into the testicular sac, which is behind the penis called the scrotum) and HIV infection are risk factors that can cause germ cell testicular tumour of the testes.
Signs and Symptoms
- Enlargement in size of the testes
- Pain in tests and scrotum
- Pain in the abdomen in case of germ cell tumour of undescended testes
- Breast enlargement in males
- Fever, night sweats, bone pains, and lethargy in cases where the cancer is spread to the other parts of the body
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis.
- Imaging techniques such as USG, CT-Scan, and MRI of pelvis and abdomen to estimate the size, size, and extent of the tumour.
- Serum alpha-fetoprotein test
- Fine needle aspiration biopsy (FNAB) of the affected testicle