What is Nodular Lymphocyte Predominant Hodgkin Lymphoma?
Nodular Lymphocyte predominant Hodgkin lymphoma is a type of Hodgkin’s lymphoma (white blood cell cancer) but it grows more slowly than classical white blood cell cancer.
Disease Epidemiology
It is approximately 5-10% of all Hodgkin’s lymphomas. It occurs in men 3 times more often than in women. The average age of onset of the disease is 30-40 years.
Disease Causes
Repetitive mutations (erroneous changes) in certain genes are thought to be responsible for the development of Hodgkin’s lymphoma with a predominance of nodular lymphocytes.
Signs and Symptoms
The patient may suffer from the following signs and symptoms. These are
- Enlarged and swollen lymph nodes
- It can also occur in children
- Very few patients can suffer from B symptoms in earlier stages of the disease. B symptoms are
- Constant fever
- Fatigue
- Night sweats
Diagnosis
The following are the diagnostic tests that help diagnose the nodular lymphocyte Predominant Hodgkin lymphoma.
- Complete blood count (CBC) with peripheral smear
- Blood coagulation profile
- Bone marrow aspiration and cytology
- Immunohistochemistry
- EBV antibodies test
- CT- scan, MRI, PET scan, Ultrasonography (USG), and X-Ray to detect the site and extent of care.
Treatment
- In cases where a person has had no signs or symptoms, only close surveillance of lymphoma is recommended.
- In early-stage (NLPHL) patients without B symptoms (persistent fever, night sweats, and weight loss), regional radiation therapy is the main treatment option.
- However, in cases where the tumor is large and causes B symptoms, chemotherapy followed by radiation therapy is the main treatment option. Other treatment options are targeted therapy and immunotherapy.
What support can we give for Nodular Lymphocyte Predominant Hodgkin Lymphoma?
Nodular lymphocyte Predominant Hodgkin Lymphoma is a rare cancer, meaning it is not as well known as other forms of cancer. Without a Ribbon is an Australian organisation that provides support for individuals who suffer from rare cancers. We provide a designated platform for Warriors to obtain information specific to their Rare Cancer. We also provide annual opportunities for our Warriors to meet and learn from each other. If you suffer from a rare cancer such as Nodular lymphocyte Predominant Hodgkin Lymphoma, we can help and support you through your journey thanks to the generous donations we receive. Click the link below to sign up and become a Warrior today!
You can help us with your donation:
Without a Ribbon is a charity that works hard to aid those who suffer from rare cancers. You can help our cause in a variety of ways: Donations — Without a Ribbon is grateful when we receive every donation. Giving to Without a Ribbon helps us to provide ongoing support, organise the annual gathering and subsidise the costs of our Warriors attending these conferences. Sponsorship — If you wish to sponsor our charity, please contact us using this form. Volunteering — We are always looking for volunteers to help with different aspects of running our charity. So, if you are looking for volunteer work, please feel free to contact us.
