What is Mesonephric like Adenocarcinoma of the Endometrium or Ovary?
Mesonephric-like Adenocarcinoma is a rare type of cancer that can develop in the uterus (endometrium) or the ovary. This cancer is “mesonephric-like” because it closely resembles mesonephric adenocarcinoma under the microscope, but it appears in areas where original mesonephric remnants are not usually found. Scientists believe that this cancer may come from normal uterine or ovarian tissue that changes into a different, more aggressive type of cell.
This cancer mostly affects adult women, especially between the ages of 40 and 70. It is not linked to HPV, and its behaviour is often more aggressive than common uterine or ovarian cancers.
Symptoms
Women with this cancer may notice unusual vaginal bleeding, especially after menopause or between periods. If the tumour is in the ovary, it may cause lower belly pain, bloating, or a lump that can be felt. Other symptoms can include weight loss, fatigue, or feeling full quickly while eating.
Diagnosis
Diagnosis is made by an ultrasound or CT scan to look at the uterus or ovaries. Blood tests may also be done. A biopsy is required to confirm the diagnosis. In this procedure, a small tissue sample is taken from the suspected tumour and examined under a microscope to look for specific cancer cells.
Treatment
Treatment usually involves surgery to remove the uterus (hysterectomy) and possibly the ovaries, depending on the location. In some cases, chemotherapy and/or radiation therapy is given after surgery to kill any remaining cancer cells and reduce the chance of it coming back.
Prognosis
Because this is a rare and aggressive cancer, early diagnosis is important. Some women respond well to treatment if the cancer is caught early. However, regular follow-up is very important, as the cancer can return in some cases.
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