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Meibomian Carcinoma

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Posted by fatima.shakeel@opmc.co | Sep 26, 2025

What is a Meibomian Carcinoma?

Meibomian Carcinoma, also known as sebaceous carcinoma, is a rare but serious cancer that begins in the oil-producing glands of the eyelids. These glands, called meibomian glands, play an important role in keeping the eyes healthy. They make a thin layer of oil that covers the surface of the eye and prevents tears from drying too quickly. When the cells of these glands start growing in an uncontrolled and abnormal way, a tumour develops.

Symptoms

This cancer is not common, but when it does occur, it is often seen in older adults, especially women. The problem with meibomian carcinoma is that in the beginning it can look very much like common eye problems, so it is often not recognized early.

At first, a person may notice a small swelling or lump in the eyelid that looks just like a stye or chalazion, which are harmless conditions. Because of this, the lump may be ignored or treated as a minor issue. However, over time, the swelling keeps increasing in size, becomes harder, and starts to behave differently than a simple stye.

As the tumour grows, it can cause several changes in the eyelid. The eyelashes may begin to fall out around the lump, the eyelid may appear thicker, red, or uneven, and sometimes the skin may become painful to touch.

The eye itself may feel irritated, watery, or uncomfortable, as though something is constantly stuck inside. In some people, the tumour presses on the eye and causes blurred vision. If left untreated for too long, the growth can break through the surface and form a wound that does not heal easily.

Diagnosis

To confirm whether a swelling in the eyelid is meibomian carcinoma, the growth is carefully examined and a small piece is taken for testing under the microscope. This step is very important, because it helps to tell the difference between harmless eyelid lumps and this dangerous cancer.

Treatment

The best treatment for meibomian carcinoma is surgery, in which the tumour is removed along with a margin of healthy tissue to make sure no cancer cells remain. If the tumour has grown very large or spread into nearby areas, more extensive surgery may be needed. In some cases, radiation therapy is also used to destroy any remaining cancer cells and prevent the disease from coming back.

Prognosis

The future outcome depends greatly on how early the cancer is found. If it is recognised in the early stage and treated properly, many people can be cured completely. But if it is ignored and left untreated, it can spread to other parts of the body, especially the lymph nodes, making it much harder to control.

In simple words, meibomian carcinoma is a dangerous eyelid cancer that may first look like an ordinary swelling. Any lump in the eyelid that does not go away should never be ignored, because catching this illness early gives the best chance for a cure and helps save both sight and life.


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