What is Mediastinal Lymphangiopericytoma?Mediastinal lymphangiopericytoma is a rare type of benign tumour that develops from the excessive multiplication or division of smooth muscle cells, endothelial cells of the lymphatic system or cells of the lymph nodes. These are more common in females. Mediastinal lymphangiopericytoma can develop in children and adults. Although it is a non-cancerous tumour if it is left untreated can produce pressure symptoms on the heart, blood vessels and lungs, it can also spread to the heart and major blood vessels of the heart.
What is Mediastinum?The mediastinum is a space in the thorax that contains the heart, thymus gland, portions of the esophagus trachea, and other structures.
Disease CausesThere is no well-known cause, however, certain hereditary and genetic mutations are considered responsible for the development of mediastinal lymphangiopericytoma.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Difficulty in breathing
- Pain in the chest
- Unexplained weight loss
- Coughing up blood in advanced and large lymphangiopericytoma tumour
DiagnosisThe following diagnostic tests and procedures can be used to make a diagnosis. These are;
- Imaging techniques like Chest X-ray, CT-scan, MRI, and PET scan to see the site, size, and extent of the tumour.
- Tumour biopsy (tumour biopsy to remove a small sample of tissue for histopathological examination)
- Sputum cytology
- USG-guided fine needle aspiration cytology