What is a Malignant Giant Cell Tumor of The Tendon Sheath?Giant cell tumor of the tendon sheath is a slowly growing painless synovial tumor within the tendon sheath. It usually affects the hands and fingers, less commonly the foot, ankle, knee, and hip.
What is a Tendon?A tendon is a structure made up of fibrous connective tissues which attach the muscles to the bones.
What is a Synovial Membrane?A synovial membrane is a thin membrane of connective tissues that lines the inner surface of joints and tendons.
Disease Etiology (Causes)There is no well-known cause; however, certain risk factors such as trauma, impaired lipid metabolism in the body, certain infections, and inflammation are believed to be responsible for the development of the tumor.
Disease EpidemiologyThe malignant giant cell tumor of the tendon sheath is the 2nd most common tumor that affects the hands and fingers after ganglion cyst. This usually occurs in people between the ages of 30 and 50 years. It is associated with degenerative joint disease.
Signs and SymptomsThe patient may suffer from the following signs and symptoms. These are
- Slowly growing hard mass in the hands, fingers, foot, ankle, knee, or hip.
- These masses are usually painless
- In rare cases, these tumor masses can cause numbness of the affected region
- The large tumor mass in the finger joint can impair its function
DiagnosisThe following diagnostic techniques and procedures can be used to make a diagnosis these are
- Diagnostic imaging techniques such as USG, CT-scan, MRI, and PET scan can be used to detect the site, size, and extent of the tumor.
- Tumor biopsy
- Histo-pathological examination